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Board of Directors

Lars Ekman, MD, Ph.D., joined Amarin as a Non-Executive Director in November 2008 and was named Amarin's Chairman of the Board of Directors effective January 2014. With more than 28-years of experience in the pharmaceutical industry, Dr. Ekman is an Executive Partner of Sofinnova Ventures. He previously served as Co-Founder and Chief Executive Officer of Cebix Inc, and prior to that he was Executive Vice President and President of Global Research and Development of Elan Corporation plc from January 2001 to December 2007. Prior to joining Elan, he was Executive Vice President, Research and Development at Schwarz Pharma AG from February 1997 to December 2000, and was previously employed in a variety of senior scientific and clinical functions at Pharmacia, now Pfizer. He serves as Executive Chairman of Sophiris Bio Inc. (formerly Protox Therapeutics) as well as Chairman of Prothena Biosciences. Dr. Ekman also sits on the Board of Directors of Cebix Inc., InterMune, and Ocera Therapeutics. Dr. Ekman is a board certified surgeon with a PhD in experimental biology and has held several clinical and academic positions in the United States and Europe. He obtained his PhD and MD from the University of Gothenburg, Sweden.

James Healy, M.D., Ph.D., joined Amarin as a Non-Executive Director in May 2008. Dr. Healy joined Sofinnova Ventures as a General Partner in 2000. Dr. Healy was a founding investor and board member of Cellective (acquired by MedImmune), CoTherix (acquired by Actelion), Novacea, and Intermune. He also serves on the boards of directors of several private companies. In the pharmaceutical industry Dr. Healy held positions at Bayer Pharmaceuticals (Miles) and ISTA Pharmaceuticals prior to its initial public offering. He began his private equity career at Sanderling. Dr. Healy earned B.A.s in Molecular Biology and Scandinavian Studies from the University of California at Berkeley, where he graduated with Distinction in General Scholarship, Honors, and received a Departmental Citation. He received his M.D. from Stanford University's School of Medicine through the Medical Scientist Training Program, and earned his Ph.D. in Immunology from Stanford University, where he was a Beckman Scholar and received a bursary award from the Novartis Foundation. Dr. Healy teaches a course on entrepreneurship at Stanford University, and is an active member of the BIO-NVCA Working Group.

Jan van Heek joined Amarin as a Non-Executive Director in February 2010. He has more than 30 years in the healthcare industry. He is currently a Principal and Partner at BioPoint Group, where he advises biotechnology and other healthcare companies in commercial strategy development, financing and business development. Prior to establishing BioPoint, Mr. van Heek spent more than 18 years at Genzyme Corporation, most recently as Senior Advisor to the CEO and senior management team. Mr. van Heek joined Genzyme in 1991, where as Executive Vice President, he was largely responsible for establishing and building its worldwide therapeutics, surgical and genetic testing businesses. Mr. van Heek is currently a board member of PanGenetics BV in the Netherlands and was a board member of and Chairman of the Audit Committee of ViaCell Corporation, a US public company, from 2002 until it was sold to Perkin Elmer Corporation in 2007. Between 2007 and 2009, he was Chairman of the Board of BioVex Inc. in Woburn, MA and where he also chaired its Audit and Compensation Committees. Mr. van Heek also served on the board of Zelos Therapeutics, Inc. between 2004 and 2008. Prior to Genzyme, Mr. van Heek held various management positions at Baxter Healthcare Corporation in Europe and the US. He received an M.B.A. from St. Gallen University, Switzerland and an executive degree from Stanford Business School, California.

Patrick O'Sullivan joined Amarin as a Non-Executive Director in December 2011. Mr. O'Sullivan has more than 40 years of pharmaceutical industry experience including more than 30 years as Chief Executive Officer and member of the Board of Directors of the LEO Pharma companies in Ireland and more than 10 years as a member of the Board of Directors of the parent company of the LEO Pharma Group in Denmark. Since 2007 he has been a business consultant to the pharmaceutical industry and he currently serves as a member of the Board of Directors of Warner Chilcott Plc. Mr. O'Sullivan earned Bachelor of Commerce and M.B.A. degrees from University College Dublin. He is a registered pharmacist, a member and honorary fellow of the Pharmaceutical Society of Ireland, and a Knight of the Order of the Dannebrog.

Kristine Peterson joined Amarin as a Non-Executive Director in November 2010. Ms. Peterson has more than 27 years of industry experience. She is currently Chief Executive Officer at Valeritas, Inc., a medical technology company dedicated to the development and commercialization of innovative drug delivery solutions, with its lead product for the treatment of diabetes. Until joining Valeritas, Ms. Peterson was Company Group Chair of Johnson & Johnson's biotech groups. Previously, she was Executive Vice President for J&J's global strategic marketing organization. Prior to J&J, Ms. Peterson was Senior Vice President, Commercial Operations for Biovail Corporation and President for Biovail Pharmaceuticals. Earlier, she spent 20 years with Bristol-Myers Squibb where she held assignments of increasing responsibility in marketing, sales, and general management, including running a cardiovascular/metabolics business unit and a generic division. Ms. Peterson is currently a director of Valeritas, Inc., ImmunoGen, Inc., the Biotechnology Industry Organization (BIO) and the Greater Philadelphia Life Sciences Congress. She is also an advisor to the Healthcare Businesswoman's Association metro chapter. She has a B.S. and an M.B.A. from the University of Illinois, Champaign-Urbana.

David Stack joined Amarin as a Non-Executive Director in December 2012. Mr. Stack is currently the President and Chief Executive Officer of Pacira Pharmaceuticals, Inc. Mr. Stack has been a managing director of MPM Capital since 2005 and a managing partner of Stack Pharmaceuticals, Inc. since 1998. From 2001 to 2004, he was President and Chief Executive Officer of The Medicines Company. Previously, Mr. Stack was President and General Manager at Innovex, Inc. He was Vice President, Business Development/Marketing at Immunomedics from 1993 until 1995. Prior to that, he was with Roche Laboratories from 1981 until 1993, in various positions including therapeutic world leader in infectious disease and director, business development and planning, infectious disease, oncology, and virology. He currently serves as a member of the board of directors of Pacira Pharmaceuticals, Inc., PepTx, Inc. and Medivo, Inc. He was a member of the boards of directors of Molecular Insight Pharmaceuticals, Inc. from 2006 to 2010 and BioClinica, Inc. from 1999 to 2010. Mr. Stack holds a B.S. in pharmacy from Albany College of Pharmacy and a B.S. in Biology from Siena College. We believe Mr. Stack's qualifications to sit on our board of directors include his extensive experience with pharmaceutical companies, his financial expertise and his years of experience providing strategic and financial advisory services to pharmaceutical and biotechnology organizations.

John Thero is Amarin's President and Chief Executive Officer. He joined Amarin in November 2009 and has more than 20 years of senior financial and operational management experience including over 15 years supporting the growth of life science companies. Mr. Thero became President and CEO of Amarin in 2014 after previously being the company's President and initially the company's Chief Financial Officer. He was appointed to the Amarin Board of Directors as of the start of 2014. Prior to Amarin, Mr. Thero was the Chief Financial Officer at ViaCell, Inc., where he helped guide the company to its successful sale, and Abiomed, Inc., during its transition from a development-stage company into a commercial entity. Mr. Thero began his professional career at Arthur Andersen LLP.

Joseph S. Zakrzewski joined Amarin in 2010 as Executive Chairman and most recently served as Amarin's CEO until the end of December 2013 when he retired from his executive roles. Mr. Zakrzewski continues to serve as a member of Amarin’s Board of Directors and also serves on the Board of Directors of Insulet Corporation and Acceleron Pharmaceuticals. Mr. Zakrzewski served as a Venture Partner with Orbimed, the world’s largest healthcare-dedicated investment firm in 2010 and 2011. Prior to this, he was Chairman, President & Chief Executive Officer of Xcellerex, a privately held company focusing on commercializing its proprietary next generation manufacturing technology for biotherapeutics and vaccines from 2007 through the first half of 2010. Mr. Zakrzewski also served as the Chief Operating Officer of Reliant Pharmaceuticals, a specialty pharmaceutical company focused on cardiovascular drugs from 2005 through the first half of 2007. From 1988 to 2004, Mr. Zakrzewski served in a variety of executive level capacities at Eli Lilly & Company including R&D, manufacturing, finance and business development. His most recent position was Vice President, Corporate Business Development, where he had global responsibility for all business development activities on a worldwide basis. Mr. Zakrzewski received a BS in Chemical Engineering in 1986, an MS in Biochemical Engineering from Drexel University in 1988, and received an MBA in Finance in 1992 from Indiana University.